MitraClip uses mechanism

MitraClip uses mechanism


MitraClip uses mechanism


[A] side-to-edge repair
[B] edge-to-top repair
[C] edge-to-edge repair
[D] side-to-side repair



MitraClip uses mechanism

  • MitraClip uses mechanism – edge-to-edge repair
  • Creation of a mechanical bridge between the midportion of the anterior and posterior mitral valve leaflets is the fundamental therapeutic mechanism,
  • Hence use of the term “edge-to-edge repair”
  • This is initially described in the surgical – Alfieri technique.
  • Edge-to-edge approximation of the middle scallop of the anterior and posterior leaflet (A2 and P2) allows the elimination of most of the mitral insufficiency while the residual smaller regurgitant jets are effectively corrected by a ring annuloplasty.

MitraClip device has been demonstrated to be successful in multiple clinical trials, including the randomized EVEREST trial.




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